For a full list of publications, see here: 

http://www.bris.ac.uk/biochemistry/people/bernadette-m-carroll/publications.html

Selected Publications:

.

2020

Carroll, B 2020, 'Spatial regulation of mTORC1 signalling: Beyond the Rag GTPases' .Seminars in Cell & Developmental Biology

https://doi.org/10.1016/j.semcdb.2020.02.007

2019

Correia-Melo, C, Birch, J, Fielder, E, Rahmatika, D, Taylor, J, Chapman, J, Lagnado, A, Carroll, BM, Miwa, S, Richardson, G, Jurk, D, Oakley, F, Mann, J, Mann, DA, Korolchuk, VI & Passos, JF, 2019, Rapamycin improves healthspan but not inflammaging in nfκb1−/− mice’. Aging Cell, vol 18

https://doi.org/10.1111/acel.12882

Kucheryavenko, O, Nelson, G, von Zglinicki, T, Korolchuk, VI & Carroll, B, 2019, ‘The mTORC1-autophagy pathway is a target for senescent cell elimination’. Biogerontology.

https://doi.org/10.1007/s10522-019-09802-9

2018

Carroll, B, Otten, EG, Manni, D, Stefanatos, R, Menzies, FM, Smith, GR, Jurk, D, Kenneth, N, Wilkinson, S, Passos, JF, Attems, J, Veal, EA, Teyssou, E, Seilhean, D, Millecamps, S, Eskelinen, EL, Bronowska, AK, Rubinsztein, DC, Sanz, A & Korolchuk, VI, 2018, ‘Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis’. Nature Communications, vol 9

https://www.nature.com/articles/s41467-017-02746-z

Carroll, B & Korolchuk, VI, 2018, ‘Nutrient sensing, growth and senescence’. FEBS Journal, vol 285., pp. 1948-1958

https://doi.org/10.1111/febs.14400

2017

Carroll, B & Korolchuk, VI, 2017, ‘Dysregulation of mTORC1/autophagy axis in senescence’. Aging, vol 9., pp. 1851-1852

https://doi.org/10.18632/aging.101277

Carroll, B*, Nelson, G, Rabanal-Ruiz, Y, Kucheryavenko, O, Dunhill-Turner, NA, Chesterman, CC, Zahari, Q, Zhang, T, Conduit, SE, Mitchell, CA, Maddocks, OD, Lovat, P, von Zglinicki, T & Korolchuk, VI*, 2017, Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing’. Journal Cell Biology 216 No. 7 1949–1957* co-corresponding author

https://doi.org/10.1083/jcb.201610113

Carroll, B & Dunlop, EA, 2017, ‘The lysosome: A crucial hub for AMPK and mTORC1 signalling’. Biochemical Journal, vol 474., pp. 1453-1466

https://doi.org/10.1042/BCJ20160780

Korolchuk, VI, Miwa, S, Carroll, B & von Zglinicki, T, 2017, Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?’. EBioMedicine, vol 21., pp. 7-13

https://doi.org/10.1016/j.ebiom.2017.03.020

2016

Hewitt, G., Carroll, B., Sarallah, R., Correia-Melo, C., Ogrodnik, M., Nelson, G., Otten, E. G., Manni, D., Antrobus, R., Morgan, B. A., von Zglinicki, T., Jurk, D., Seluanov, A., Gorbunova, V., Johansen, T., Passos, J. F. & Korolchuk, V. I., 2016, SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.  Autophagy. 12, 10, p.1917-1930

https://doi.org/10.1080/15548627.2016.1210368 

Ward, C., Martinez-Lopez, N., Otten, E. G., Carroll, B., Maetzel, D., Singh, R., Sarkar, S. & Korolchuk, V. I., 2016, Autophagy, lipophagy and lysosomal lipid storage disorders.  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1861, 4, p.269-284

https://doi.org/10.1016/j.bbalip.2016.01.006

Correia-Melo, C., Marques, F. D. M., Anderson, R., Hewitt, G., Hewitt, R., Cole, J., Carroll, B. M., Miwa, S., Birch, J., Merz, A., Rushton, M. D., Charles, M., Jurk, D., Tait, S. W. G., Czapiewski, R., Greaves, L., Nelson, G., Bohlooly-Y, M., Rodriguez-Cuenca, S., Vidal-Puig, A. et al, 2016, Mitochondria are required for pro-ageing features of the senescent phenotype. EMBO Journal. 35, 7, p.724-742

https://doi.org/10.15252/embj.201592862 

Carroll, B., Maetzel, D., Maddocks, O. D. K., Otten, G., Ratcliff, M., Smith, G. R., Dunlop, E. A., Passos, J. F., Davies, O. R., Jaenisch, R., R.Tee, A., Sarkar, S. & Korolchuk, V. I., 2016, Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity . eLife.  e11058

https://doi.org/10.7554/eLife.11058

2014

Lu, W., Zhang, Y., McDonald, D. O., Jing, H., Carroll, B., Robertson, N., Zhang, Q., Griffin, H., Sanderson, S., Lakey, J. H., Morgan, N. V., Reynard, L. N., Zheng, L., Murdock, H. M., Turvey, S. E., Hackett, S. J., Prestidge, T., Hall, J. M., Cant, A. J., Matthews, H. F. et al, 2014, Dual proteolytic pathways govern glycolysis and immune  competence. Cell, 159, 7, p.1578-1590

https://doi.org/10.1016/j.cell.2014.12.001

2013

Sarkar, S., Carroll, B., Buganim, Y., Maetzel, D., Ng, A. H. M., Cassady, J. P., Cohen, M. A., Chakraborty, S., Wang, H., Spooner, E., Ploegh, H., Gsponer, J., Korolchuk, V. I. & Jaenisch, R., 2013, Impaired autophagy in the lipid-storage disorder niemann-pick type c1 disease. Cell Reports. 5, 5, p.1302-1315

https://doi.org/10.1016/j.celrep.2013.10.042

Carroll, B., Hewitt, G. & Korolchuk, V. I., 2013, Autophagy and ageing: Implications for age-related neurodegenerative diseases. Essays in Biochemistry. 55, 1, p.119-131

https://doi.org/10.1042/BSE0550119

Carroll, B., Mohd-Naim, N., Maximiano, F., Frasa, M. A., McCormack, J., Finelli, M., Thoresen, S. B., Perdios, L., Daigaku, R., Francis, R. E., Futter, C., Dikic, I. & Braga, V. M. M., The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy 2013, Developmental Cell. 25, 1, p.15-28

https://doi.org/10.1016/j.devcel.2013.03.005

 

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